Last updated: April 2025 · Reading time: ~12 min
Lid margin disease refers to chronic irritation, inflammation, or dysfunction along the edge of the eyelid where the eyelashes and oil glands are located. It may involve blepharitis, meibomian gland dysfunction, lash-line buildup, tear film instability, dry eye symptoms, redness, burning, grittiness, watery eyes, or recurring eyelid discomfort. In Demodex blepharitis, mites living around the lash follicles may contribute to collarettes, cylindrical dandruff, lash debris, lid margin inflammation, and an unhealthy eyelid environment. This section explains how lid margin disease may connect with Demodex-related eyelid concerns and what visible lash-line clues can help identify recurring irritation patterns.